El Blog De La Enfermera

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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">GENERALIDADES DEL SNA</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Neuronas preganglionares colinérgicas,        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Neuronas postganglionares simpáticas o parasimpáticas.        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">En la inervación simpática hay una excepción, la inervación de la glándula sudorípara, en la cual la neurona postganglionar es colinérgica.        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Inervación de la glándula suprarrenal,        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Tamaño de las neuronas preganglionares simpáticas y parasimpáticas.        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh6.ggpht.com/-j6neV5ulivc/ToKWjv2NEVI/AAAAAAAAAnc/7chQVOxedwg/s1600-h/clip_image004%25255B4%25255D.jpg"><img alt="clip_image004" border="0" height="209" src="http://lh5.ggpht.com/-nP53HnXe1DU/ToKWmBz-ByI/AAAAAAAAAng/uaJMmNKTnK8/clip_image004_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image004" v:shapes="_x0000_i1026" width="325" /></a></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">        </span></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">FUNCIONES DEL SNA</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh5.ggpht.com/-uUNHOJVKk0s/ToKWnGx-YJI/AAAAAAAAAnk/QrryXNIgAcs/s1600-h/clip_image006%25255B4%25255D.jpg"><img alt="clip_image006" border="0" height="257" src="http://lh3.ggpht.com/-sr-BWkzol4Y/ToKWoIt8IgI/AAAAAAAAAno/_UGSp5Pq0I4/clip_image006_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image006" v:shapes="Imagen_x0020_2" width="384" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh5.ggpht.com/-GPeFzrK4ydE/ToKWpDrydkI/AAAAAAAAAns/hEqflXBPv5E/s1600-h/clip_image008%25255B4%25255D.jpg"><img alt="clip_image008" border="0" height="351" src="http://lh4.ggpht.com/-tqU5Q0GyUyY/ToKWqJ_pFzI/AAAAAAAAAnw/wEakai21MVg/clip_image008_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image008" v:shapes="_x0000_i1028" width="379" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">SISTEMA PARASIMPATICO            </span></b></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">SÍNTESIS Y LIBERACIÓN DE ACH</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Síntesis:</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> Acetiltransferasa        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Almacenamiento:</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> Captación en vesículas, protege la AcH de la degradación.        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Liberación:</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> bloqueada por la toxina botulínica,<span style="mso-spacerun: yes;">  </span>el veneno de araña la induce.         </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Unión al receptor            </span></b></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Degradación</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> por la Acetilcolinesterasa (AcHE) rápidamente en la hendidura sináptica        </span></div>
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<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Reciclaje de colina.</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh4.ggpht.com/-usUN_viJqkY/ToKWq_HKqWI/AAAAAAAAAn0/0mTraMXmkhY/s1600-h/clip_image010%25255B4%25255D.jpg"><img alt="clip_image010" border="0" height="95" src="http://lh6.ggpht.com/-VJdMlbfMIwc/ToKWroGp10I/AAAAAAAAAn4/-2rEfr8Eh34/clip_image010_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image010" v:shapes="Imagen_x0020_3" width="376" /></a></span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">RECEPTORES COLINÉRGICOS</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<b><span lang="FR" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: fr; mso-font-kerning: 12.0pt;">Receptores ionotrópicos (</span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Nicotínico)            </span></b></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh6.ggpht.com/-OJon2Phanzs/ToKWsYF2M9I/AAAAAAAAAn8/iXYETVx6U90/s1600-h/clip_image012%25255B4%25255D.gif"><img alt="clip_image012" border="0" height="294" src="http://lh5.ggpht.com/-R0zfW8lv1JY/ToKWtWu15zI/AAAAAAAAAoA/W5Q6yosKwSw/clip_image012_thumb%25255B2%25255D.gif?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image012" v:shapes="Objeto_x0020_5" width="330" /></a></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">        </span></div>
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<b><span lang="FR" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: fr; mso-font-kerning: 12.0pt;">Receptores metabotrópicos (Muscarínico)</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh4.ggpht.com/-lmvuUdlIe44/ToKWuHSh-QI/AAAAAAAAAoE/qRvU4mujsKs/s1600-h/clip_image014%25255B4%25255D.gif"><img alt="clip_image014" border="0" height="290" src="http://lh5.ggpht.com/-S91tsRAXacY/ToKWu7YfqGI/AAAAAAAAAoI/rbTH7vu6-Yk/clip_image014_thumb%25255B2%25255D.gif?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image014" v:shapes="Objeto_x0020_6" width="322" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">NICOTÍNICO</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">     <br />Afinidad: Nicotina > Acetilcolina > Muscarina         </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh4.ggpht.com/-3sv-QwOi1GQ/ToKWv97Or9I/AAAAAAAAAoM/60pUWowKl_Q/s1600-h/clip_image016%25255B4%25255D.jpg"><img alt="clip_image016" border="0" height="156" src="http://lh5.ggpht.com/-GEpqH1HUVps/ToKWwwUvU3I/AAAAAAAAAoQ/uo5o-ejyBtQ/clip_image016_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image016" v:shapes="_x0000_i1032" width="346" /></a></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">        </span></div>
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<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"><strong>MUSCARÍNICO</strong><span style="mso-spacerun: yes;"><strong> </strong>                              </span>         </span></div>
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<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Afinidad: Muscarina > Acetilcolina > Nicotina        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh6.ggpht.com/-CGt9f0YUhao/ToKWyLo7aQI/AAAAAAAAAoU/WIzrjXNOlco/s1600-h/clip_image018%25255B6%25255D.jpg"><img alt="clip_image018" border="0" height="262" src="http://lh6.ggpht.com/-Tw3sw0rndsE/ToKWzApnDiI/AAAAAAAAAoY/qd7BlfXmpeA/clip_image018_thumb%25255B4%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image018" v:shapes="Imagen_x0020_4" width="370" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Acciones Muscarínicas mediadas por AcH</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh6.ggpht.com/-hgY8Tw6PkCE/ToKWz6hoQmI/AAAAAAAAAoc/gGAPs70Ahk8/s1600-h/clip_image020%25255B4%25255D.jpg"><img alt="clip_image020" border="0" height="211" src="http://lh4.ggpht.com/-fqSk-cktp-o/ToKW00VKSTI/AAAAAAAAAog/YK0mgIoIDEw/clip_image020_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image020" v:shapes="Imagen_x0020_5" width="369" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">MECANISMO DE ACCIÓN</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ACETILCOLINA:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l9 level1 lfo3; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Compuesto de Amonio cuaternario.        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">No puede atravesar las membranas celulares.        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Carece de relevancia terapéutica, debido a que produce numerosas acciones y la inactiva la AcHE con rapidez.        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">SISTEMA CARDIOVASCULAR            </span></b></div>
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<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh6.ggpht.com/-B1R6zNBSzY0/ToKW3KWbTtI/AAAAAAAAAos/5RYwW7CSmVc/s1600-h/clip_image024%25255B5%25255D.jpg"><img alt="clip_image024" border="0" height="212" src="http://lh4.ggpht.com/-mpY7jz9RtQk/ToKW354yG_I/AAAAAAAAAow/sDEavvkV78k/clip_image024_thumb%25255B3%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image024" v:shapes="Imagen_x0020_8" width="376" /></a></span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">            </span></b></div>
<ol style="margin-top: 0cm;" type="1">
<li class="MsoNormal" style="mso-list: l2 level1 lfo4; tab-stops: list 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">Disminución de la FC y del GC: </span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Vía IV atenuación breve de la FC como resultado de una reducción de la frecuencia de emisión del nodo SA.            </span></li>
<li class="MsoNormal" style="mso-list: l2 level1 lfo4; tab-stops: list 36.0pt;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">Disminución de la Presión Arterial: </span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></li>
</ol>
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<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">A dosis bajas de Acetilcolina (2</span><span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-bidi-font-weight: bold; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: symbol;"><span style="mso-char-type: symbol; mso-symbol-font-family: symbol;">m</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">g) </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> vasodilatación generalizada con hipotensión y taquicardia refleja.</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">         </span></div>
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<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"><span style="mso-tab-count: 1;">            </span>Por estimulación de <span style="mso-bidi-font-weight: bold;">receptores M<sub>3</sub> </span>en el músculo liso del endotelio </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> aumento del calcio intracelular a través de la cascada de los fosfoinositoles </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> activación de una calmodulina que es importante para la acción de la óxido nítrico-sintasa </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"><span style="mso-spacerun: yes;">  </span>síntesis de óxido nítrico a partir de L-arginina </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> activación de una guanidil-ciclasa soluble </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> aumento de CMPc </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> salida de calcio </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> relajación </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> dicha vasodilatación produce hipotensión </span><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> taquicardia refleja.</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">A dosis altas de acetilcolina (50</span><span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-bidi-font-weight: bold; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: symbol;"><span style="mso-char-type: symbol; mso-symbol-font-family: symbol;">m</span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">g.) </span><span style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">         </span></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"><span style="mso-tab-count: 1;">            </span>Porque disminuye la despolarización en su fase 4, por lo cual retarda la llegada del potencial de membrana; a <span style="mso-bidi-font-weight: bold;">nivel del nodo AV</span>, aumenta el período refractario y produce un retardo en la conducción; <span style="mso-bidi-font-weight: bold;">sobre e</span>l <span style="mso-bidi-font-weight: bold;">músculo auricular </span>produce acortamiento del potencial de acción; y sobre el <span style="mso-bidi-font-weight: bold;">músculo ventricular </span>los efectos son escasos, ya que posee poca inervación colinérgica.          </span></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">DEPENDENCIA DEL ENDOTELIO PARA LA VASODILATACIÓN POR ACETILCOLINA.</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l0 level1 lfo5; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">•<span style="font: 7pt "Times New Roman";">      </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Aorta de conejo donde se encuentra una población de músculo liso con noradrenalina, con dosis crecientes acetilcolina<span style="mso-spacerun: yes;">  </span></span><span style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"> relajación del músculo liso.         </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l0 level1 lfo5; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">•<span style="font: 7pt "Times New Roman";">      </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Si eliminamos el endotelio mediante frotamiento, se produce contracción con noradrenalina y la dosis creciente de acetilcolina es incapaz de producir relajación (no hay M3).         </span></div>
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<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh4.ggpht.com/-q3rDP8A6L4g/ToKW4gnHGmI/AAAAAAAAAo0/qV7-jzYvCus/s1600-h/clip_image026%25255B4%25255D.jpg"><img alt="clip_image026" border="0" height="310" src="http://lh5.ggpht.com/-P2jlwsVsyMg/ToKW5d2JZgI/AAAAAAAAAo4/eZY6wA75LRA/clip_image026_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image026" v:shapes="Imagen_x0020_9" width="295" /></a></span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">PREPARACIÓN IN SITU EN UN ANIMAL</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l17 level1 lfo6; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">AcH 2</span><span lang="ES-TRAD" style="font-family: symbol; mso-ansi-language: es-trad; mso-ascii-font-family: calibri; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: calibri; mso-symbol-font-family: symbol;"><span style="mso-char-type: symbol; mso-symbol-font-family: symbol;">m</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">g (dosis baja) se produce vasodilatación, con la consecuente disminución de la presión arterial, proceso mediado por los receptores M<sub>3</sub> y una taquicardia refleja como mecanismo compensador;          </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l17 level1 lfo6; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Dosis Mayor (50</span><span lang="ES-TRAD" style="font-family: symbol; mso-ansi-language: es-trad; mso-ascii-font-family: calibri; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: calibri; mso-symbol-font-family: symbol;"><span style="mso-char-type: symbol; mso-symbol-font-family: symbol;">m</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">g) la hipotensión es más marcada por un mayor estímulo de receptores M<sub>3</sub>, y además es suficiente para estimular receptores muscarínicos M<sub>2</sub> en el corazón produciendo bradicardia por inhibición de adenilciclasa, apertura de canales de K<sup>+</sup> (que produce la hiperpolarización).          </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l17 level1 lfo6; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Con dosis de 2mg. de atropina (bloqueante no selectivo de los M), La PA: queda normal (porque los vasos poseen receptores M, mas no inervación parasimpática), la FC: aumenta porque predomina la inervación simpática por bloqueo del receptor M<sub>2.</sub> </span><span lang="ES-TRAD" style="font-family: wingdings; mso-ansi-language: es-trad; mso-ascii-font-family: calibri; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: calibri; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> Desequilibrio autonómico.         </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l17 level1 lfo6; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">AcH (5mg.) posteriormente a la administración de atropina (encontrándose los receptores muscarínicos ocupados por el antagonista), la acetilcolina actuará sobre los receptores nicotínicos en la Gandula suparrenal </span><span lang="ES-TRAD" style="font-family: wingdings; mso-ansi-language: es-trad; mso-ascii-font-family: calibri; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: calibri; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> NA aumentando de la presión arterial y la frecuencia cardíaca. </span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpLast">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh6.ggpht.com/-uYkRIHLCHI4/ToKW6CLf2wI/AAAAAAAAAo8/ClBAMIkgdQg/s1600-h/clip_image028%25255B3%25255D.jpg"><img alt="clip_image028" border="0" height="144" src="http://lh3.ggpht.com/-WPdLBXdvJ5A/ToKW62ONTVI/AAAAAAAAApA/Otv0kHUx4iA/clip_image028_thumb%25255B1%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image028" v:shapes="Imagen_x0020_11" width="233" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"><span style="mso-spacerun: yes;"> </span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh5.ggpht.com/-dBsR0ISNF8o/ToKW7tLcqnI/AAAAAAAAApE/8-MQZWi3D48/s1600-h/clip_image030%25255B3%25255D.jpg"><img alt="clip_image030" border="0" height="109" src="http://lh4.ggpht.com/-uP4RxolJugo/ToKW8ZNwedI/AAAAAAAAApI/I8uY120fY-Y/clip_image030_thumb%25255B1%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image030" v:shapes="Imagen_x0020_10" width="244" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">AGONISTAS MUSCARINICOS</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">ACCION DIRECTA            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Acetilcolina y esteres sintéticos de la colina:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l8 level1 lfo7; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">1.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Metacolina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l8 level1 lfo7; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">2.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Carbacol        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l8 level1 lfo7; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">3.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Betanecol        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Alcaloides naturales:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l7 level1 lfo8; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">1.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Pilocarpina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l7 level1 lfo8; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">2.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Muscarina        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l7 level1 lfo8; text-indent: -18pt;">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">3.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">Arecolina</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ACCIÓN INDIRECTA            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Reversible:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">1.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Edrofonio        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">2.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Piridostigmina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">3.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Neostigmina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">4.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Fisostigmina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">5.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Ambeninio        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">6.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Ecotiofato        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l23 level1 lfo9; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">7.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Tacrine        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Irreversible:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l20 level1 lfo10; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">1.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Diisopropil fosfofluorifato (DFP)        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l20 level1 lfo10; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">2.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Paratión y Paraoxón (insecticidas de uso agrícola)        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l20 level1 lfo10; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">3.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Samón y Sarín (de uso militar)        </span></div>
<div class="MsoNormal">
<b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">REACTIVACION DE LA<span style="mso-spacerun: yes;">  </span>ACETILCOLINESTERASA</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<ol style="margin-top: 0cm;" type="1">
<li class="MsoNormal" style="mso-list: l11 level1 lfo11; tab-stops: list 36.0pt;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Pralidoxima </span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></li>
<li class="MsoNormal" style="mso-list: l11 level1 lfo11; tab-stops: list 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Obidoxima:            </span></li>
</ol>
<div class="MsoNormal">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">     </span></div>
<br />
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">   </span><br />
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">ACCION DIRECTA </span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"> Esteres sintéticos de la colina            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh4.ggpht.com/-qqruHDiraBI/ToKW9hhnpEI/AAAAAAAAApM/O_G22_H2oD8/s1600-h/clip_image032%25255B4%25255D.jpg"><img alt="clip_image032" border="0" height="253" src="http://lh3.ggpht.com/-8uxGwmTG8U0/ToKW-zh9GyI/AAAAAAAAApQ/9pymSlpkrV4/clip_image032_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image032" v:shapes="Imagen_x0020_6" width="380" /></a></span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">ACCION DIRECTA </span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"> Alcaloides naturales            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh3.ggpht.com/-bd9CLYe8prc/ToKW_zIBdlI/AAAAAAAAApU/g_juNCnW3Rw/s1600-h/clip_image034%25255B4%25255D.jpg"><img alt="clip_image034" border="0" height="231" src="http://lh4.ggpht.com/-PxIqHIWbyKk/ToKXA9EeJjI/AAAAAAAAApY/4YtpXVGuMEk/clip_image034_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image034" v:shapes="_x0000_i1041" width="385" /></a></span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ACCIÓN INDIRECTA </span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> Reversibles             </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh5.ggpht.com/-YBVlMTqPf58/ToKXCJFmidI/AAAAAAAAApc/Bd0GQxWsm7E/s1600-h/clip_image036%25255B4%25255D.jpg"><img alt="clip_image036" border="0" height="254" src="http://lh5.ggpht.com/-k_uFzT7Acns/ToKXDIDWFLI/AAAAAAAAApg/Pp5LhAYXi1U/clip_image036_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image036" v:shapes="_x0000_i1042" width="391" /></a></span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ACCIÓN INDIRECTA </span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: wingdings; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-ascii-font-family: arial; mso-bidi-font-family: arial; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: arial; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span></b><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> Irreversibles             </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ORGANOFOSFORADOS:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l16 level1 lfo12; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Diisopropil fosfofluorifato (DFP)        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l16 level1 lfo12; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Paratión y Paraoxón (insecticidas        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l16 level1 lfo12; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">de uso agrícola)        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l16 level1 lfo12; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Samón y Sarín (de uso militar)        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l16 level1 lfo12; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Inhiben irreversiblemente la AcHE y producen un cuadro de intoxicación, ya que la AcH será capaz de estimular sus receptores<span style="mso-spacerun: yes;">  </span>(muscarínicos y nicotínicos) por un tiempo prolongado.         </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l16 level1 lfo12; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Son MUY liposolubles y atraviesan cualquier barrera</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">EFECTOS ADVERSOS</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">      <br /><span style="mso-spacerun: yes;"> </span>(de los inhibidores de la AcHE)         </span></div>
<div class="MsoNormal">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-weight: bold; mso-font-kerning: 12.0pt;">Llevan a una activación Colinérgica generalizada:</span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh4.ggpht.com/-C4WXfp9FzXM/ToKXEORhf5I/AAAAAAAAApk/pRzz3rteaKk/s1600-h/clip_image038%25255B5%25255D.jpg"><img alt="clip_image038" border="0" height="262" src="http://lh6.ggpht.com/-OlmQKoOE4Yk/ToKXFJeTa4I/AAAAAAAAApo/OzXvboez0MA/clip_image038_thumb%25255B3%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image038" v:shapes="_x0000_i1043" width="412" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">TRATAMIENTO DE LA INTOXICACÍON</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Medidas generales:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l15 level1 lfo13; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Soporte de las funciones Vitales        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l15 level1 lfo13; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Lavado Gástrico con </span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">carbón activado asociado o no a catárticos</span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l15 level1 lfo13; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">No inducir emesis        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l15 level1 lfo13; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Descontaminación: lavado de piel y mucosas.        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l15 level1 lfo13; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Tto de las convulsiones: Diazepam IV (5-10mg)        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Atropina:             </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l18 level1 lfo14; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">2-4mg IV lentamente.        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l18 level1 lfo14; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">2 mg cada 5 minutos </span><span lang="ES-TRAD" style="font-family: wingdings; mso-ansi-language: es-trad; mso-ascii-font-family: calibri; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: calibri; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> hasta 200mg/día.        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l18 level1 lfo14; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Pralidoxima: Infusion IV1-2gm en 15-30 minutos.        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l18 level1 lfo14; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Obidoxima: IV 3-6mg/kg durante 5-10 minutos.        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ANTAGONISTAS COLINÉRGICOS</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Se clasifican en base a su mecanismo de acción:        </span></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l4 level1 lfo15; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">1.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Bloqueantes de los receptores muscarínicos.        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l4 level1 lfo15; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">2.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Inhibidores de la síntesis de acetilcolina:        </span></div>
<div class="MsoListParagraphCxSpMiddle">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Inhibición de la recaptación.        </span></div>
<div class="MsoListParagraphCxSpMiddle">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Inhibición de la colina acetil-tranferasa.        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l4 level1 lfo15; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-fareast-font-family: arial; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">3.<span style="font: 7pt "Times New Roman";">    </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Inhibidores de la liberación de acetilcolina        </span></div>
<div class="MsoNormal">
<span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Solo el grupo uno tiene usos terapéuticos, los otros dos solamente lo tienen experimental</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">BLOQUEANTES DE LOS RECEPTORES MUSCARÍNICOS</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">FARMACOCINÉTICA            </span></b></div>
<table border="1" cellpadding="0" cellspacing="0" class="MsoNormalTable" style="border-bottom: medium none; border-collapse: collapse; border-left: medium none; border-right: medium none; border-top: medium none; mso-border-alt: solid black .5pt; mso-border-insideh: .5pt solid black; mso-border-insidev: .5pt solid black; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt; mso-yfti-tbllook: 1184; width: 315.35pt;"><tbody>
<tr style="height: 32.6pt; mso-yfti-firstrow: yes; mso-yfti-irow: 0;">       <td style="border-bottom: black 1pt solid; border-left: black 1pt solid; border-right: black 1pt solid; border-top: black 1pt solid; height: 32.6pt; mso-border-alt: solid black .5pt; padding-bottom: 0cm; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0cm; width: 148.85pt;" valign="top" width="198"><div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; text-align: center;">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">AMINAS                            </span></b></div>
<div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; text-align: center;">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">TERCIARIAS                            </span></b></div>
</td>        <td style="border-bottom: black 1pt solid; border-left: medium none; border-right: black 1pt solid; border-top: black 1pt solid; height: 32.6pt; mso-border-alt: solid black .5pt; mso-border-left-alt: solid black .5pt; padding-bottom: 0cm; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0cm; width: 166.5pt;" valign="top" width="222"><div align="center" class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; text-align: center;">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">AMINAS CUATERNARIAS                            </span></b></div>
</td>     </tr>
<tr style="height: 104pt; mso-yfti-irow: 1; mso-yfti-lastrow: yes;">       <td style="border-bottom: black 1pt solid; border-left: black 1pt solid; border-right: black 1pt solid; border-top: medium none; height: 104pt; mso-border-alt: solid black .5pt; mso-border-top-alt: solid black .5pt; padding-bottom: 0cm; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0cm; width: 148.85pt;" valign="top" width="198"><ul style="margin-top: 0cm;" type="disc">
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">Absorción rápida                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span lang="EN-US" style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: en-us; mso-font-kerning: 12.0pt;">Unión a pp 50 %</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span lang="EN-US" style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: en-us; mso-font-kerning: 12.0pt;">Tmax 1 hora</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">T1/2 4 horas                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">Parcialmente metabolizado en hígado                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">> biodisponibilidad                             </span></li>
</ul>
</td>        <td style="border-bottom: black 1pt solid; border-left: medium none; border-right: black 1pt solid; border-top: medium none; height: 104pt; mso-border-alt: solid black .5pt; mso-border-left-alt: solid black .5pt; mso-border-top-alt: solid black .5pt; padding-bottom: 0cm; padding-left: 5.4pt; padding-right: 5.4pt; padding-top: 0cm; width: 166.5pt;" valign="top" width="222"><ul style="margin-top: 0cm;" type="disc">
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">Escasa absorción gastroentestinal                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">Poca penetración al SNC                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">Bloque receptores muscarinicos                             </span></li>
<li class="MsoNormal" style="line-height: normal; margin-bottom: 0pt; mso-list: l5 level1 lfo16; tab-stops: 36.0pt;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; mso-font-kerning: 12.0pt;">Acción más selectiva del tubo digestivo                             </span></li>
</ul>
</td>     </tr>
</tbody></table>
<div class="MsoNormal" style="margin-bottom: 0pt;">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">AMINAS TERCIANAS:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Atropina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Escopolamina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Homatropina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Telencepina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Pirencepina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Tripitramina        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l12 level1 lfo17; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Darifenacina        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">AMINAS CUATERNARIAS:            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l14 level1 lfo18; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Bromuro de Ipratropio,         </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l14 level1 lfo18; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Bromuro de Tiotropio</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l14 level1 lfo18; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Metilnitrato de atropina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l14 level1 lfo18; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Metilbromiro de escopolamina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l14 level1 lfo18; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Metilbromuro de homotrapina        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l14 level1 lfo18; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Bloqueantes de los receptores muscarínicos</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpMiddle">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh3.ggpht.com/-nVkJZXrOSgg/ToKXGEWMkVI/AAAAAAAAAps/HywRI97frH0/s1600-h/clip_image040%25255B4%25255D.jpg"><img alt="clip_image040" border="0" height="229" src="http://lh3.ggpht.com/-JIRFJLm6ivA/ToKXHAaA88I/AAAAAAAAApw/TZ5RXNR9CuM/clip_image040_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image040" v:shapes="_x0000_i1044" width="362" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpMiddle">
<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-fareast-language: es; mso-font-kerning: 12.0pt; mso-no-proof: yes;"><a href="http://lh3.ggpht.com/-dnlYL3BFxHw/ToKXICBYVcI/AAAAAAAAAp0/LhnjXW67I8E/s1600-h/clip_image042%25255B4%25255D.jpg"><img alt="clip_image042" border="0" height="214" src="http://lh6.ggpht.com/-rfBj5dxR_fw/ToKXJSHCkEI/AAAAAAAAAp4/7BrbeKfnt_Q/clip_image042_thumb%25255B2%25255D.jpg?imgmax=800" style="border-bottom: 0px; border-left: 0px; border-right: 0px; border-top: 0px; display: block; float: none; margin-left: auto; margin-right: auto;" title="clip_image042" v:shapes="_x0000_i1045" width="367" /></a></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ATROPINA</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l6 level1 lfo19; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Alcaloide de la Atropa Belladona con alta afinidad por receptores muscarinicos, se une de competitivamente tanto a los centrales como a los periféricos.        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l6 level1 lfo19; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">La dosis ordinaria máxima es de 1g.        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Duración:</span></b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;"> cuatro horas (excepto de forma tópica que puede durar días).        </span></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Farmacocinética:            </span></b></div>
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<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-EC" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-ec; mso-font-kerning: 12.0pt;">El inicio de la actividad atropínica es a los 30 minutos por vía IM y entre 2 a 4 minutos por vía IV.</span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l6 level1 lfo19; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Se metaboliza de forma parcial en el hígado.        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l6 level1 lfo19; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Eliminación: orina (>).        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l6 level1 lfo19; text-indent: -18pt;">
<span lang="ES-TRAD" style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">T1/2: 4 horas.        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">USOS TERAPEUTICOS</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l22 level1 lfo20; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Oftálmico:</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"> Midriasis y cicloplejía</span><span style="font-family: wingdings; mso-ascii-font-family: calibri; mso-char-type: symbol; mso-font-kerning: 12.0pt; mso-hansi-font-family: calibri; mso-symbol-font-family: wingdings;"><span style="mso-char-type: symbol; mso-symbol-font-family: wingdings;">à</span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"> facilita la medición de errores de refracción sin interferencia de los movimientos de acomodación.        </span></div>
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<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Antiespasmódico:</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"> relaja tracto gastrointestinal.        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l22 level1 lfo20; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Coadyuvante en la anestesia general.</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l22 level1 lfo20; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Antídotos para agonistas colinérgicos:</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"> Intoxicación por organofosforados, veneno de algunos hongos.        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l22 level1 lfo20; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Hiperactividad parasimpática:</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;"> En Miastenia Gravis (para evitar efectos muscarínicos).        </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">REACCIONES ADVERSAS</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">     <br />(Dosis dependientes)         </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">Bloqueo Periférico            </span></b></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">1º grado </span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">(Dosis baja): Sequedad de la boca, depresión de la secreción traqueobronquial, hipertensión.         </span></div>
<div class="MsoNormal">
<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;"> 2º grado: </span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">Midriasis, visión borrosa, perturbación de la acomodación, anormalidades en la conducción cardiaca.         </span></div>
<div class="MsoNormal">
<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;"> 3º grado</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">: Retención urinaria <span style="mso-spacerun: yes;"> </span>         </span></div>
<div class="MsoNormal">
<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Bloqueo Central             </span></b></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">1º grado</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">: Cambios del humor y alteraciones de la marcha.        </span></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">2ª grado: </span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Alteraciones en la memoria.        </span></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">3ª grado: </span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Desorientación y alucinaciones.        </span></div>
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<b style="mso-bidi-font-weight: normal;"><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">ESCOPOLAMINA</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoListParagraphCxSpFirst" style="mso-list: l13 level1 lfo21; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Alcaloide natural        </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l13 level1 lfo21; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Produce efectos periféricos similares a los de la atropina         </span></div>
<div class="MsoListParagraphCxSpMiddle" style="mso-list: l13 level1 lfo21; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Mayor efecto sobre el SNC, y su duración de acción es mas larga.        </span></div>
<div class="MsoListParagraphCxSpLast" style="mso-list: l13 level1 lfo21; text-indent: -18pt;">
<span style="font-family: symbol; font-size: 12pt; line-height: 115%; mso-bidi-font-family: symbol; mso-fareast-font-family: symbol; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">·<span style="font: 7pt "Times New Roman";">         </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Gran afinidad por los 5 receptores muscarínicos.        </span></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">Usos:</span></b><b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">            </span></b></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l21 level1 lfo22; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Cinetosis (prevención del vertigo de traslacion),<span style="mso-spacerun: yes;">  </span>         </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l21 level1 lfo22; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Bloqueo de la memoria anterograda.</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">         </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l21 level1 lfo22; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Sedación (pero a dosis altas puede producir excitación).         </span></div>
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<b style="mso-bidi-font-weight: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">BROMURO DE IPRATROPIO            </span></b></div>
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<span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Derivado sintético cuaternario, usado en enfermedades pulmonares crónicas y obstructivas debido a que <i>carece de acciones centrales, no atraviesa la BHE.            </i></span></div>
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<b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-bidi-font-style: italic; mso-font-kerning: 12.0pt;">Acciones: </span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l19 level1 lfo23; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Broncodilatador         </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l19 level1 lfo23; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Taquicardias         </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l19 level1 lfo23; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">Disminuye secreciones        </span></div>
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<b><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Usos:</span></b><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l1 level1 lfo24; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Asma cronica persistente</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l1 level1 lfo24; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Asma o bronquitis por ejercicio o por irritantes,</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l1 level1 lfo24; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Bronquitis cronica </span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">        </span></div>
<div class="MsoNormal" style="margin-left: 36pt; mso-list: l1 level1 lfo24; tab-stops: list 36.0pt; text-indent: -18pt;">
<span style="font-family: "Times New Roman","serif"; font-size: 12pt; line-height: 115%; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 12.0pt;"><span style="mso-list: ignore;">-<span style="font: 7pt "Times New Roman";">          </span></span></span><span lang="ES-TRAD" style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-ansi-language: es-trad; mso-font-kerning: 12.0pt;">Exacerbacion de asma severa (junto con agonistas B2)</span><span style="font-family: "Arial","sans-serif"; font-size: 12pt; line-height: 115%; mso-font-kerning: 12.0pt;">.        </span></div>

COLINÉRGICOS Y ANTICOLINÉRGICOS

GENERALIDADES DEL SNA · Neuronas preganglionares colinérgicas, · Neuronas postganglionares simpáti...

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